AN ANALOGUES-BASED FORECASTING SYSTEM FOR MEDITERRANEAN MARINE-LITTER CONCENTRATION


Curation and expansion of the Human Phenotype Ontology for systemic autoinflammatory diseases improves phenotype-driven disease-matching

IntroductionAccurate and standardized phenotypic descriptions are essential in diagnosing rare diseases and discovering new diseases, and the Human Phenotype Ontology (HPO) system was developed to provide a rich collection of hierarchical A Resilience Engineering Approach for the Risk Assessment of IT Services phenotypic descriptions.However, altho

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A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy.

Gemcitabine is among the most efficacious and widely used antimetabolite agents.Its molecular targets are ribonucleotide reductase M1 (RRM1) and elongating DNA.Acquired and de novo resistance as a result of RRM1 overexpression are major obstacles to therapeutic efficacy.We deployed a synthetic lethality screen to investigate if knockdown of 87 sele

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The signature of SARS-CoV-2-related genes predicts the immune therapeutic response and prognosis in breast cancer

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an exceptionally contagious single-stranded RNA virus with a strong positive contagion.The COVID-19 pandemic refers to the swift worldwide dissemination of SARS-CoV-2 infection, which began in late 2019.The COVID-19 epidemic has disrupted many cancer treatments.A few reports i

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